Scientist/Senior Scientist – T Cell Biologist

Laguna Hills, CA, USA

About the Role

The Antibody Therapeutics team is seeking a highly motivated Scientist/Senior Scientist to perform discovery research and early drug development in the area of cancer immunology. The successful candidates will implement and apply cellular immunology with focus on T cell biology, biochemistry and mouse models to characterize immunotherapeutic, and will be expected to make intellectual and technical contributions.


Ph.D. or M.S. in Immunology/ Cell Biology with a strong focus in T cell biology and/or myeloid cell with industrial and/or academic research experiences. Highly motivated, highly detailed-oriented, willing to work in a small company. In-depth knowledge and direct experiences in T cell biology skills such as Flow Cytometry, primary cell isolation and sorting, T cell assays, ELISA, DNA molecular cloning, RT-PCR, and data analysis are a must. Experiences in single-cell sequencing, DNA library construction, Biacore SPR, and Octet BLI are a plus.

Excellent communication and problem-solving skills. Proven ability to work independently in a fast-paced team environment.

Key Responsibilities

  • Perform protein expression and purification for in vitro and in vivo experiments
  • Assist in method development for protein purification protocols
  • Maintain detailed documentation of experimental results and reagent inventory
  • Perform routine maintenance of protein purification and analysis instruments
  • Perform analytical experiments to determine protein quality


Salary range is commensurate with skills and experience, plus competitive fringe benefits and generous stock options.

We offer 401(k) retirement plan, health care and dependent care FSA.

About the Company

Amberstone Biosciences is a preclinical biotherapeutic company located in Orange County, California. We discover transformative immunotherapeutic antibodies including bispecific and multispecific molecules that uniquely address tumor microenvironment in part through developing highly innovative single-cell functional discovery platform technology. We believe that innovation is the foundation of our successes and our employees are the most valuable assets. We welcome people with adventurous spirits to join us, grow with us and prosper with us.