Director/Senior Director of Immuno-Oncology

Laguna Hills, CA, USA

About the Role
Amberstone Biosciences, Inc. is seeking an experienced and highly motivated Director to lead a research group focusing on the development of our proprietary tumor microenvironment activated novel therapeutic biologics for the treatment of cancer. Reporting to the CTO/SVP of Therapeutic Biologics, the Director of Immuno-Oncology is a key leadership position and an exciting opportunity to advance our current next generation immunotherapeutics into the clinic. The successful candidate is a passionate and rigorous scientist, an effective leader, a great team player, and thrives in a fast-paced, results-driven environment managing multiple projects and scientists.


  • PhD degree and 10+ years of experience in immunology, cancer biology, cell biology, and/or molecular biology with previous experience in biologics drug discovery
  • Strong knowledge base in immunology and/or cancer immunology, with expertise in T cell biology preferred
  • Broad technical skill sets in molecular and cell biology, including human and/or mouse primary cell culture, multi-parameter flow cytometry, immunological assays, single cell transcriptomics, cell line development, in vivo animal study design/execution
  • Attention to details with strong organizational and record keeping skills
  • Excellent communications and interpersonal skills
  • Key Responsibilities

  • Build and manage a highly productive team of Research Associates and/or Scientists to advance current therapeutic programs
  • Execute and refine the drug research strategy, help to move lead molecules into IND filing with helps from internal and external collaborations
  • Keep abreast of current trend and knowledge in therapeutic targets and related biology
  • Lead the research efforts in early discovery research: design, conduct, and analyze in vitro and in vivo experiments in therapeutic molecule screening and identification, lead characterization, mechanism of action and pharmacological activity studies
  • Act as cross-functional project team leader if needed
  • Contribute to a culture that embraces continuous learning, development, and collaboration
  • Represent the company in significant scientific meetings
  • Salary/Benefits

    Salary range is commensurate with skills and experience, plus competitive fringe benefits and generous stock options.

    We offer 401(k) retirement plan, health care and dependent care FSA.

    About the Company

    Amberstone Biosciences is a preclinical biotherapeutic company located in Orange County, California. We discover transformative immunotherapeutic antibodies including bispecific and multispecific molecules that uniquely address tumor microenvironment in part through developing highly innovative single-cell functional discovery platform technology. We believe that innovation is the foundation of our successes and our employees are the most valuable assets. We welcome people with adventurous spirits to join us, grow with us and prosper with us.