Associate Scientist/Scientist – Antibody Discovery & Engineering

Laguna Hills, CA, USA

About the Role

We are seeking a highly motivated Associate Scientist/Scientist in the Antibody Engineering group at Amberstone Biosciences. The main responsibilities include DNA/RNA prep, molecular cloning, cell culture and characterization of antibodies by ELISA and SPR.


  • M.S. or Ph.D. degree in Molecular Biology or a related discipline with 3+ years of industry and/or academic experience.
  • Highly motivated, willing to work in an early-stage company, eager to learn/develop molecular cell biology techniques and drug development processes.
  • Knowledge/expertise in molecular and cell biology skills such as DNA and RNA isolation, construct cloning, RT-PCR, sequencing, data analysis and cell-based assays. Experiences in hybridoma or single B cell cloning, ELISA, Biacore SPR and/or Octet BLI are a plus.
  • Excellent communication and problem-solving skills are required. Attention to details is a must. Proven ability to work in a fast-paced team environment is necessary.
  • Key Responsibilities

  • Discovery antibodies via different platforms
  • Engineering differentiated lead molecules including antibodies, multispecific, cytokines, or fusion proteins
  • Optimize therapeutic antibodies through humanization, affinity maturation, and manufacturability engineering
  • Work with Biology and Protein Science group to advance our pipeline development
  • Salary/Benefits

    Salary range is commensurate with skills and experience, plus competitive fringe benefits and generous stock options.

    We offer 401(k) retirement plan, health care and dependent care FSA.

    About the Company

    Amberstone Biosciences is a preclinical biotherapeutic company located in Orange County, California. We discover transformative immunotherapeutic antibodies including bispecific and multispecific molecules that uniquely address tumor microenvironment in part through developing highly innovative single-cell functional discovery platform technology. We believe that innovation is the foundation of our successes and our employees are the most valuable assets. We welcome people with adventurous spirits to join us, grow with us and prosper with us.